Love totalspaces!
Only missing thing for me is a hotkey to switch between displays. I would to be able to navigate the spaces individually for each display without having to touch the mouse 
One thing you can do is to tell TotalSpaces2 to use the active screen rather than the one containing the mouse for switching. See here: http://totalspaces.binaryage.com/defaults-settings2 (“Use active screen for switching”)
Secondly, if you use the overview grid, you can navigate using the cursor keys, and hit enter to change space to the highlighted one. You can use tab to swap between screens when viewing the overview grid.