Asepsis on non-sytem internal HDD

Is it possible to enable Asepsis to do its magic on a non-system internal HDD? I run my OS X Yosemite installation off an external USB3 SSD. The HDD built into my iMac is where I store my large amount of data. Asepsis is keeping the system disk clean of .DS_Store files. However, it’s not keeping the built-in HDD clean. Am I missing something that needs to be enabled? Or is this functionality not available at all? If the latter, perhaps this could be an enhancement addition for an upcoming release version.